COVID-19 trials registries data warehouse

http://www.ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=43400

Anupam Prakash

prakashanupam@hotmail.com

2020-04-30

Recruiting

RCT

Randomized

Parallel

Not reported

single-center

Treatment

â?¢ Adult patients (â?¥18years) suffering from mild or very mild Covid-19 (8). A positive throat swab for nCoV-2019 (by real time PCR) obtained from a patient suspected to be Covid-19 or from a contact (or HCW) of Covid-19 patient will be considered to be a Covid-19 case, irrespective of the presence of symptoms. Mild disease will be defined as respiratory rate between 12-18/minute and SpO2 â?¥ 95% in room air and no clinico-radiological (normal chest X-ray) signs of pneumonia.

â?¢ Patients with renal or hepatic dysfunction (Serum creatinine > 1.5 mg/dL and serum transaminase levels >120 U/L) <br/ >â?¢ Patients with clinical heart failure/known CAD <br/ >â?¢ Known cases of neoplasms or immunodeficiency syndromes <br/ >â?¢ Patients who are on chemotherapy, immunosuppressive agents, steroids or antiviral agents, or have received in the preceding 4 weeks <br/ >â?¢ Pregnant and lactating patients <br/ >â?¢ Uncooperative patients (in the opinion of the investigator, if it is difficult to ensure patient cooperation during the study) <br/ >

2

Lady Hardinge Medical College

18

99

India

Mild disease at enrollment

1: Mild disease at enrollment

48

Proportion of patients having virologic cure on Day 6 in both the groupsTimepoint: Day 6 of treatment initiation

| Declared number of arm (2.0) differs from found arms (3.0)

Phase 2

[{"arm_notes": "", "treatment_id": 883, "treatment_name": "Niclosamide", "treatment_type": "Antiparasitics", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]