COVID-19 trials registries data warehouse

http://www.chictr.org.cn/showproj.aspx?proj=53658

Fengjie Xie

mdjxfj1971@126.com

2020-05-15

Recruiting

RCT

Randomized

Parallel

Not reported

single-center

Treatment

1. Aged 2 to 65 years old, and signed informed consent, 2. According to the diagnostic criteria of the New Coronavirus Pneumonia Diagnosis and Treatment Program (Trial Version 7) issued by the National Health and Health Commission, those who have been diagnosed with CoVID-19 of light and common type and have been treated with hydroxychloroquine and Abidol but nCoV Nucleic acid did not turn negative. The specific diagnostic criteria are as follows: (1) light type: The clinical symptoms are mild, and there is no pneumonia manifestation in imaging, (2) Common type: It has fever, respiratory tract and other symptoms. Pneumonia can be seen on imaging, (3) The patient who have been diagnosed with CoVID-19 of light and common type and have been treated with hydroxychloroquine and Abidol but nCoV Nucleic acid did not turn negative.

1. Pregnant women within 3 months of pregnancy, 2. Patients with liver and kidney disease and those with liver and kidney injury 3. Patients with blood diseases (such as leukopenia, thrombocytopenia, etc.). 4. Electrocardiogram prompting patients with severely extended QT.

2

Hongqi Hospital Affiliated to Mudangjiang Medical University

2

65

China

Mild/moderate disease at enrollment

2: Mild/moderate disease at enrollment

240

Tolerance;Viral load of nCoV;Blood routine;Immunological examination;Blood liver and kidney function test;Myocardial enzyme biochemical examination;ECG examination;Urine routine;body temperature;pulse;Breathe;blood pressure;CT examination of the lungs;

| Declared number of arm (2.0) differs from found arms (3.0)

Phase 4

[{"arm_notes": "", "treatment_id": 120, "treatment_name": "Artemisinin-piperaquine", "treatment_type": "Antimalarials", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]