COVID-19 trials registries data warehouse

http://www.chictr.org.cn/showproj.aspx?proj=51647

Prof. Qingsong Ye

20215851@qq.com

2020-03-27

Not recruiting

RCT

Randomized

Parallel

Not reported

single-center

Treatment

(1) Aged 18-65 years, (2) Voluntarily participate in this clinical trial and sign off informed consent form , (3) Diagnosed with severe pneumonia of COVID: respiratory distress, RR >30 times / min, resting oxygen saturation of 93% or less, arterial partial pressure of oxygen / oxygen concentration 300mmHg, SARS-CoV-2 nucleic acid test was positive. (4) Chest imaging confirm COVID-19 featured changes in lung.

(1) Receive any clinical trial drug treatment for COVID-2019 within 30 days before the screening assessment, (2) Severe liver disease (e.g., Child Pugh score >=C or AST> 5 times of the upper limit), (3) Patients with known severe renal insufficiency (estimated glomerular filtration rate <=30mL / min/1.73 m2) or patients receiving continuous renal replacement therapy, hemodialysis, peritoneal dialysis, (4) Co-infection of HIV, hepatitis B, tuberculosis, influenza virus, adenovirus or other respiratory infection viruses, (5) Female patients who have no sexual protection in the last 30 days prior to the screening assessment, (6) Pregnant or lactating women or women using estrogen contraception, (7) Patients who are planning to become pregnant during the study period or within 6 months after the end of the study period, (8) Other conditions that the researchers consider inappropriate for participating in this clinical trial.

2

Renmin Hospital of Wuhan University

18

65

China

Severe disease at enrollment

6: Severe disease at enrollment

20

TTCI;

| Declared number of arm (2.0) differs from found arms (3.0)

Not reported

[{"arm_notes": "", "treatment_id": 594, "treatment_name": "Human dental pulp stem cells", "treatment_type": "Advanced therapy medicinal products (atmp)", "pharmacological_treatment": "Biological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]