COVID-19 trials registries data warehouse

http://www.chictr.org.cn/showproj.aspx?proj=50059

Le Aiping

leaiping@126.com

2020-02-24

Recruiting

RCT

Randomized

Parallel

Not reported

single-center

Treatment

1) The confirmed patient (or legal guardian) agrees to participate in the study and signs the informed consent form, 2) aged 18 to 65 years, 3) Real-time fluorescent RT-PCR of respiratory specimens or blood specimens to detect patients with new type of coronavirus positive, 4) Patients diagnosed as severe and critically ill and with rapid disease progression according to the Diagnosis and Treatment Program for Pneumonia of New Coronavirus Infection (Trial Version 6) .

1) Any situation where the solution cannot be carried out safely, 2) Allergic constitution, allergic to plasma or drugs, 3) Being too old with severe underlying diseases that affect survival, including uncontrolled clinically significant heart, lung, kidney, digestive, hematological, neuropsychiatric, immune, metabolic, or malignant tumors, Severe malnutrition, etc., 4) Patients with severe respiratory failure, heart failure, and multiple organ failure, 5) Participants in other clinical trials.

2

The First Affiliated Hospital of Nanchang University

18

65

China

Severe disease at enrollment

6: Severe disease at enrollment

100

Cure rate;Mortality;

| Declared number of arm (2.0) differs from found arms (3.0)

Phase 1

[{"arm_notes": "", "treatment_id": 322, "treatment_name": "Convalescent plasma", "treatment_type": "Convalescent plasma", "pharmacological_treatment": "Biological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]