COVID-19 trials registries data warehouse

http://www.chictr.org.cn/showproj.aspx?proj=49747

Xiaoguang Tong

Tongxg@yahoo.com

2020-02-23

Recruiting

RCT

Randomized

Parallel

Not reported

multi-center

Treatment

1. Aged 18-80 years, 2. Within 1 week of onset, 3. Meet the diagnostic criteria of common, severe and critical NCP, according to Pneumonitis Diagnosis and Treatment Scheme for Novel Coronavirus Pneumonia (Trial Version 6) . 4. Sign informed consent.

1. Any situation that does not allow the program to proceed safely, 2. The patient may be transferred to a non-participating hospital within 72 hours, 3. Those who have continued to use immunosuppressive agents or organ transplants for the past 6 months, 4. Glucose-6-phosphate dehydrogenation Enzyme deficiency (faba bean disease) 5, 5. Patients treated with any of the antiviral drugs listed in the protocol during hospitalization before enrollment, 6. Those participating in other clinical trials. 7. Those who are allergic to ozone or hypersensitive.

2

Tianjin Huanhu Hospital

18

80

China

Moderate/severe/critical disease at enrollment

5: Moderate/severe/critical disease at enrollment

180

Chest imaging;RNA test of COVID-19;Time to remission/disappearance of primary symptoms: defined as the number of days when the three main symptoms of fever; cough; and shortness of breath are all relieved / disappeared;Completely antipyretic time: completely antipyretic was defined as the body temperature return to normal for over 24 hours.;Blood oxygen saturation;Time to 2019-nCoV RT-PCR negativity: defined as the last test time for two consecutive negative respiratory viral nucleic acid tests (sampling interval of at least 1 day);Liver; renal and heart function;

| Declared number of arm (6.0) differs from found arms (7.0)

Phase 0

[{"arm_notes": "", "treatment_id": 951, "treatment_name": "Ozonated autohemotherapy", "treatment_type": "Life support", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]