COVID-19 trials registries data warehouse

http://www.chictr.org.cn/showproj.aspx?proj=49720

Feng Cao

fengcao8828@163.com

2020-02-18

Not recruiting

RCT

Randomized

Parallel

Not reported

multi-center

Treatment

1. Aged >=60 years, 2. Patients confirmed with novel coronavirus pneumonia. The Diagnostic criteria refer to Pneumonitis Diagnosis and Treatment Scheme for Novel Coronavirus Infection (Trial Version 5) , 3. Those without broad-spectrum antibacterial, antifungal, and antiviral treatment, 4. Imaging revealed pneumonia in patients with a diagnosis of pathogen: influenza, CAP/HAP bacterial infection, and fungal infection, 5. Participants signed informed consent before the study, 6. It must be agreed not to participate in other clinical studies until the 28th day of completion.

1. critically ill patients based on the New Protocol for Diagnosis and Treatment of NCP, 2. Patients with eye diseases (such as cataract, conjunctivitis, glaucoma) 3. Severe liver disease (such as AST > 3 ULN), 4. Patients with severe renal insufficiency (estimated glomerular filtration rate <=30ml/min/1.73m2) or continuous renal replacement therapy, hemodialysis or peritoneal dialysis, 5. Pregnant or breast-feeding women, 6. Patients may be transferred to non-designated hospitals within 72 hours, 7. Patients who have participated in other clinical trials in the past 7 days, 8. Allergic constitution, such as those who are allergic to two or over twodrugs ,with history of food allergies, or known to be allergic to the ingredients of this drug, 9. In the opinion of the investigator, subjects who are not suitable for enrollment or with any factors that affect the outcome of the trial.

2

Chinese PLA General Hospital

60

None

China

Moderate disease at enrollment

3: Moderate disease at enrollment

300

Arterial Blood Oxygen Saturation;TTCR;Time to Clinical recovery;temperature;respiratory rate;Lung CT;

| Declared number of arm (2.0) differs from found arms (3.0)

Phase 4

[{"arm_notes": "", "treatment_id": 665, "treatment_name": "Interferon alpha1b", "treatment_type": "Interferons", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]