COVID-19 trials registries data warehouse

http://www.chictr.org.cn/showproj.aspx?proj=48777

Yaokai Chen

yaokaichen@hotmail.com

2020-01-29

Recruiting

RCT

Randomized

Parallel

Not reported

single-center

Treatment

1. Male or female over 18 years of age, 2. Novel coronavirus infection is confirmed by pathogenic detection, 3. The diagnosis of severe coronavirus pneumonia will have to meet at least one of the following criteria: (1) Respiratory distress, RR>30 times/minute (2) In the state of no oxygen at rest, the patient's SPO2<=93% (3) Oxygenation Index (PaO2/FiO2)<=300 mmHg (1mmHg=0.133kPa), (4) Respiratory failure requiring mechanical ventilation, (5) Sepsis, (6) Other organ failure requiring ICU care. 4. Be willing to give the informed consent.

1. Patients are allergic or intolerant to therapeutic drugs, 2. Pregnancy or lactating women, 3. Researchers believe that patients may have other factors affecting the efficacy or safety evaluation of this study.

2

Chongqing Public Health Medical Center

18

None

China

Severe/critical disease at enrollment

7: Severe/critical disease at enrollment

48

SOFA score;

| Declared number of arm (2.0) differs from found arms (3.0)

Not reported

[{"arm_notes": "", "treatment_id": 798, "treatment_name": "Methylprednisolone", "treatment_type": "Corticosteroids", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]