| Trial registration number
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NCT05171985 |
Full text link
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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https://clinicaltrials.gov/show/NCT05171985
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First author
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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Amr Elbadry
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Contact
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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amrarafa009@gmail.com
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Registration date
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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2021-12-29
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Recruitment status
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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Not recruiting
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Study design
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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RCT
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Allocation
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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Randomized
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Design
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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Parallel
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Masking
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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Blind label
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Center
Last imported at : March 15, 2023, 4 a.m.
Source : ClinicalTrials.gov
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single-center
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Study aim
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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Treatment
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Inclusion criteria
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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inclusion criteria:
patients age ≥18 years
confirmed to have covid-19 pneumonia by nasopharyngeal swab pcr together with chest radiology
requiring invasive mechanical ventilation.
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Exclusion criteria
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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heart rate <50 beats per minute,
atrioventricular conduction block of grade ii or iii,
mean arterial pressure (map) <55 mmhg (despite appropriate intravenous volume replacement and vasopressor treatment),
acute severe neurological disorder,
propofol or dexmedetomidine allergy or other contraindications.
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Number of arms
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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2
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Funding
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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Tanta University
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Inclusion age min
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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18
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Inclusion age max
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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80
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Countries
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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Egypt
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Type of patients
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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Critical disease at enrollment
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Severity scale
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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8: Critical disease at enrollment
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Total sample size
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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144
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primary outcome
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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The number of atrial fibrillation (AF) attacks
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Notes
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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None
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Phase
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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Not reported
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Arms
Last imported at : Dec. 31, 2021, 5 a.m.
Source : ClinicalTrials.gov
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[{"arm_notes": "", "treatment_id": 1878, "treatment_name": "Dexmedetomidine", "treatment_type": "Central nervous system agents", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]
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