| Trial registration number
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NCT04871633 |
Full text link
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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https://clinicaltrials.gov/show/NCT04871633
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First author
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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Not reported
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Contact
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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Not reported
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Registration date
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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2021-05-04
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Recruitment status
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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Completed
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Study design
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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RCT
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Allocation
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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Randomized
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Design
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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Parallel
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Masking
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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Open label
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Center
Last imported at : March 15, 2023, 4 a.m.
Source : ClinicalTrials.gov
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single-center
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Study aim
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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Treatment
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Inclusion criteria
Last imported at : Nov. 16, 2021, 6:30 p.m.
Source : ClinicalTrials.gov
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inclusion criteria:
all patients with confirmed covid-19 of either gender and aged 12 years and above.
patients having severe covid 19 disease. severe disease is defined as patients with an oxygen saturation (spo2) ≤94% on room air or requiring supplemental oxygen or requiring mechanical ventilation or requiring extracorporeal membrane oxygenation (ecmo).17
-
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Exclusion criteria
Last imported at : Nov. 16, 2021, 6:30 p.m.
Source : ClinicalTrials.gov
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known severe allergic reaction to remdesivir or to other antiviral drugs
patients already having other treatments like tocilizumab or other antiviral drugs
pregnancy or breastfeeding
alanine aminotransferase (alt) or aspartate aminotransferase (ast) >5 times upper normal limit
creatinine clearance <30ml/min
low platelet count <50,000/l
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Number of arms
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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2
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Funding
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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King Edward Medical University
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Inclusion age min
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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12
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Inclusion age max
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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100
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Countries
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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Pakistan
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Type of patients
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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Severe disease at enrollment
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Severity scale
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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6: Severe disease at enrollment
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Total sample size
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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66
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primary outcome
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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Hospital Stay;Ventilation
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Notes
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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None
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Phase
Last imported at : Nov. 16, 2021, 6:30 p.m.
Source : ClinicalTrials.gov
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Not reported
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Arms
Last imported at : May 5, 2021, 11:25 a.m.
Source : ClinicalTrials.gov
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[{"arm_notes": "", "treatment_id": 1099, "treatment_name": "Remdesivir", "treatment_type": "Antivirals", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]
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