COVID-19 trials registries data warehouse

https://clinicaltrials.gov/show/NCT04341285

Peter Rosenberger, Prof

peter.rosenberger@med.uni-tuebingen.de

2020-04-10

Withdrawn

RCT

Randomized

Parallel

Open label

single-center

Treatment

inclusion criteria: - covid-19positive(+) ards as defined according to the berlin definition - ratio of partial pressure arterial oxygen and fraction of inspired oxygen (pao2/ fio2) ≤100 - bilateral opacities consistent with pulmonary edema on frontal chest radiograph - requirement for positive pressure ventilation via an endotracheal tube or non-invasive ventilation - no clinical evidence of left atrial hypertension, or if measured, a pulmonary arterial wedge pressure (paop) less than or equal to 18 mmhg. - ≤ 7 days from the initiation of mechanical ventilation at the time of randomization. - patients must be enrolled within 96 hours of onset of ards -

- covid-19negative(-) ards - age less than 18 years - more than 7 days since initiation of mechanical ventilation - more than 96 hours since meeting ards criteria - patient, surrogate or physician not committed to full intensive care support. - pregnancy

2

University Hospital Tuebingen

18

None

Germany

Severe/critical disease at enrollment

7: Severe/critical disease at enrollment

0

28 day all cause mortality

None

Not reported

[{"arm_notes": "Early implantation", "treatment_id": 440, "treatment_name": "Ecmo", "treatment_type": "Life support", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "Late implantation", "treatment_id": 440, "treatment_name": "Ecmo", "treatment_type": "Life support", "pharmacological_treatment": "Non pharmacological treatment"}]