COVID-19 trials registries data warehouse

https://clinicaltrials.gov/show/NCT04623385

Mahmoud Elkazzaz, B.Sc in Biochemistry

mahmoudramadan2051@yahoo.com

2020-11-10

Unknown

RCT

Randomized

Parallel

Open label

unclear

Treatment

inclusion criteria: - adult sari patients with 2019-ncov infection confirmed by pcr; absolute value of lymphocytes < 0. 6x 109/l; severe respiratory failure within 48 hours and requires admission to icu. (severe respiratory failure was defined as pao2/fio2 < 200 mmhg and was supported by positive pressure mechanical ventilation (including non-invasive and invasive mechanical ventilation, peep>=5cmh2o))

age < 18 pregnant allergic to experimental drugs and patients have the following conditions: - hypercholesterolemia - hypertriglyceridemia - liver disease - renal disease - sjögren syndrome - pregnancy - lactation - depressive disorder - body mass index less than 18 points or higher than 25 points - contraindications for hormonal contraception or intrauterine device. - autoimmune diseases a history of organ, bone marrow or hematopoietic stem cell transplantation - patients receiving anti-hcv treatment - permanent blindness in one eye - history of iritis, endophthalmitis, scleral inflammation or retinitis 15-90 days of retinal detachment or eye surgery - known malignant disease, psa > 3 ug/l, nycturia > 3 times - the competent physician considered it inappropriate to participate in the study

2

Kafrelsheikh University

18

70

None

Critical disease at enrollment

8: Critical disease at enrollment

1000

lung injury score

None

Phase 4

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