COVID-19 trials registries data warehouse

https://clinicaltrials.gov/show/NCT04603690

Prof. Dr. Ikram Din Ujjan, MBBS, PhD

ikramujjan@lumhs.edu.pk

2020-10-27

Completed

RCT

Randomized

Parallel

Open label

single-center

Treatment

inclusion criteria: patients must be 18 years of age or older, of either gender patients must be tested positive for sars-cov-2 by rt-pcr within 72 hours prior to enrolment patients must exhibit typical symptoms of covid-19 disease at screening such as fever, fatigue, a dry and contagious cough, loss of appetite, body aches, shortness of breath, mucus or phlegm, sore throat, headache, chills, sometimes with shaking, loss of smell or taste, congestion or runny nose, nausea, or vomiting, diarrhea, muscular pain etc. patients must be in the early stage of covid-19 disease who do not require hospitalization at the time of screening patients must be under the care of a physician for diagnosis of covid-19 patients who have signed informed consent

patients with proven hypersensitivity or allergic reaction to quercetin or curcumin patients with known chronic kidney disease with estimated creatinine clearance < 50 ml/minute or need for dialysis patients who are severely hypotensive defined as needing hemodynamic pressors to maintain blood pressure patients taking anticoagulant/antiplatelet drugs such as coumarine, heparine, aspirin, clopidrogel, dalteparin, enoxaparin, ticlopidine and warparin. patients with gallstone obstruction hypothyroid suffering patients patients with moderate or severe thrombocytopenia (platelet count <100 ×10⁹/l); pregnant patients

2

Liaquat University of Medical & Health Sciences

18

100

Pakistan

Moderate/severe disease at enrollment

4: Moderate/severe disease at enrollment

50

COVID-19 symptoms improvement;SARS-CoV-2 Negativity by RT-PCR

None

Not reported

[{"arm_notes": "nan", "treatment_id": 1476, "treatment_name": "Curcumin+quercetin+vitamin d3", "treatment_type": "Vitamins and dietary supplements+others pharmacological treatment", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "nan", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]