COVID-19 trials registries data warehouse

https://clinicaltrials.gov/show/NCT05694962

Lirong Wu, M.D, Ph.D

wulirong126@126.com

2023-01-23

Not recruiting

RCT

Randomized

Parallel

Open label

multi-center

Treatment

inclusion criteria: have had a positive test confirming the diagnosis of covid-19; have had clinical signs of severe acute respiratory syndrome or pneumonia (dyspnea, cough, with need for oxygen support at the time of enrollment); have visible consolidations/ground glass opacities on chest x-ray or computed tomography; have been on ventilator support for no longer than 5 calendar days prior to the schedule date of delivery of low-dose radiation therapy; they voluntarily participate in this clinical trial, gave informed consent and signed the informed consent form.

have received chest radiotherapy before bacteria, fungi and other infections other than novel coronavirus infection; combined with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney, hematopoietic and endocrine system or immune system diseases (the upper limit of liver function alt and ast> normal reference value, the upper limit of scr> normal reference value, poor blood glucose control); mental retardation, mental disorders; planned pregnancy, pregnancy, lactation women and during the trial; allergy constitution or allergy to the drug ingredients and excipients of this test; participated in other clinical trials in the recent 1 month; the investigator does not considered appropriate to participate in this clinical trial.

2

Jiangsu Cancer Institute & Hospital

40

85

None

Severe disease at enrollment

6: Severe disease at enrollment

40

Clinical improvement

None

Phase 2

[{"arm_notes": "nan", "treatment_id": 746, "treatment_name": "Low dose radiation therapy", "treatment_type": "Radiation therapy", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "nan", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]