COVID-19 trials registries data warehouse

https://clinicaltrials.gov/show/NCT05677932

Joey WY Chan

joeywychan@cuhk.edu.hk

2023-01-10

Recruiting

RCT

Randomized

Parallel

Blind label

single-center

Long covid

inclusion criteria: age 18 or above capable to give informed consent covid-19 infection confirmed by pcr test or a rapid antigen test (rat) with onset of at least three months reports new onset or exacerbation of fatigue after onset of covid-19 and lasted for over two months scoring 7 or above for the item "worst level of fatigue during the last 24 hours" in the brief fatigue inventory

a current or past history of bipolar disorder, schizophrenia, neurodevelopmental disorder, organic mental disorder; intellectual disabilities or substance use disorder. presence of contraindications to bright light therapy: for example, history of light induced migraine/ epilepsy; current use of photosensitizing medications; presence of eye disease: e.g. retinal blindness, severe cataract, glaucoma. significant medical condition/ hearing impairment/ speech deficit leading to incapability of completing clinical interview. regular shift-workers trans-meridian flight in the past 3 months and during the study currently receiving any structured psychotherapy self-reported untreated sleep disorders (e.g. severe insomnia, obstructive sleep apnea, restless leg syndrome), psychiatric illness (e.g. depression), or medical conditions associated with fatigue (e.g. anemia, heart failure, autoimmune disorders) enrolment in another clinical trial of an investigational medicinal product or device.

2

Chinese University of Hong Kong

18

100

Hong Kong

Patients recovered from covid

N/A

36

Change of fatigue symptoms

None

Not reported

[{"arm_notes": "Bright light therapy", "treatment_id": 2385, "treatment_name": "Light therapy", "treatment_type": "Medical device", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "Dim red light therapy", "treatment_id": 2385, "treatment_name": "Light therapy", "treatment_type": "Medical device", "pharmacological_treatment": "Non pharmacological treatment"}]