| Trial registration number
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IRCT20110510006431N6 |
Full text link
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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http://en.irct.ir/trial/66460
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First author
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Afshin Zarghi
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Contact
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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azarghi@yahoo.com
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Registration date
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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2022-10-29
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Recruitment status
Last imported at : May 22, 2023, 4 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Completed
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Study design
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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RCT
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Allocation
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Randomized
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Design
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Parallel
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Masking
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Blind label
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Center
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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single-center
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Study aim
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Treatment
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Inclusion criteria
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Age above 18 years
The presence of shortness of breath
Positive PCR test for corona or lung involvement in imaging
Signing informed consent and readiness to participate in the plan
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Exclusion criteria
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Patients suffering from underlying diseases including pulmonary hypertension, kidney failure, seizures, depression, chronic hepatitis, cirrhosis and cholestatic liver diseases and pulmonary embolism (in the past 3 months)
Use of anti-coagulant drugs such as warfarin, hormonal drugs and other illegal drugs (within the past 30 days)
Alcohol consumption
Pregnancy or breastfeeding
Allergy to AAT drug
Having IgA deficiency
No smoking in the last 6 months
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Number of arms
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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2
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Funding
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Shahid Beheshti University of Medical Sciences
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Inclusion age min
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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18
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Inclusion age max
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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100
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Countries
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Iran
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Type of patients
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Mild disease at enrollment
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Severity scale
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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1: Mild disease at enrollment
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Total sample size
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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50
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primary outcome
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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the ratio of neutrophils to lymphocytes
ESR
CRP
IL-6
Mortality rate
hospitalization time
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Notes
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Phase
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Phase 3
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Arms
Last imported at : Nov. 2, 2022, 1:22 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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[{"arm_notes": "", "treatment_id": 1951, "treatment_name": "Alpha one antitrypsin", "treatment_type": "Coagulation modifiers", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]
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