COVID-19 trials registries data warehouse

https://clinicaltrials.gov/show/NCT05518474

Not reported

Not reported

2022-08-26

Terminated

RCT

Randomized

Parallel

Open label

single-center

Treatment

inclusion criteria: age ≥18 years positive sars-cov-2 pcr test presence of two or more of the following criteria: age>55 years fever by history or at presentation cough dyspnea/shortness of breath fatigue necessitating daytime bed rest one or more of the following medical conditions: hypertension diabetes cardiovascular disease chronic lung disease chronic kidney disease obesity (bmi≥30kg/m2) tachycardia > 110 bpm oxygen saturation <94% one or more of the following laboratory abnormalities: lymphocytes <1500/microl esr > 100 mm/h crp > 10 mg/l d-dimer > 1000 ng/ml ldh > 240 u/l bilateral infiltrates or ground glass opacities on chest x-ray or ct scan socially and medically fit for discharge access to a smartphone

pregnancy >20/40 weeks body mass index (bmi) >40 kg/m2. skeletal deformities that interfere with proning developmental delay or cognitive impairment that would preclude patient cooperation other contraindications to proning including any of the following: recent abdominal surgery, active vomiting, acute intoxication. unlikely to adhere to the proning protocol according to the treating physician's judgment fully vaccinated for covid-19

2

Unity Health Toronto

18

100

Canada

Moderate/severe disease at enrollment

4: Moderate/severe disease at enrollment

11

Composite of hospitalization and all cause mortality

None

Not reported

[{"arm_notes": "nan", "treatment_id": 1181, "treatment_name": "Self-prone positioning", "treatment_type": "Respiratory support", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "nan", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]