COVID-19 trials registries data warehouse

https://clinicaltrials.gov/show/NCT04517123

Mahendra Damarla

mdamarl1@jhmi.edu

2020-08-18

Completed

RCT

Randomized

Parallel

Open label

multi-center

Treatment

inclusion criteria: - age ≥ 18 years - covid-19 positive by nasopharyngeal swab or serostatus - use of supplemental oxygen or respiratory rate ≥ 20

- bmi ≥ 45 kg/m2 - pregnancy - chest tube placement - hemodynamic instability with mean arterial pressure < 60 mmhg - thoracic or abdominal wounds - chest wall deformities - vertebral column deformities that would preclude prone positioning - facial trauma or surgery in the last 30 days - established diagnosis of interstitial lung disease - prior single or double lung transplant - surgery for spine, femur, or pelvis in the last 3 months - thoracic or cardiac surgery in the last 30 days - pacemaker placement last 7 days

2

Johns Hopkins University

18

100

United States

Moderate disease at enrollment

3: Moderate disease at enrollment

35

Occurrence of an escalation in respiratory related care (yes vs no)

None

Not reported

[{"arm_notes": "nan", "treatment_id": 1027, "treatment_name": "Prone position", "treatment_type": "Respiratory support", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "nan", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]