| Trial registration number
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IRCT20220517054899N1 |
Full text link
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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http://en.irct.ir/trial/64354
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First author
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Vajehallah Raeesi
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Contact
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Vajehraeesi@yahoo.com
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Registration date
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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2022-08-13
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Recruitment status
Last imported at : March 22, 2023, 8 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Completed
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Study design
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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RCT
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Allocation
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Randomized
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Design
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Parallel
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Masking
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Open label
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Center
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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single-center
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Study aim
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Treatment
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Inclusion criteria
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Definitive diagnosis of Covid-19 based on taking a sample from the pharynx and PCR laboratory confirmation
Lung involvement more than 50%
SPO2 levels below 80% without oxygen or below 88% with oxygen or IL above 10 or ferritin above 1500
Patients who have not responded to other Covid-19 treatments
Age over 18 years and consent to participate in the study
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Exclusion criteria
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
History of albumin sensitivity
Heparin allergy who cannot receive heparin as an anticoagulant during plasmapheresis
Patients with hypocalcemia (citrate used in the plasmapheresis process exacerbates hypocalcemia)
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Number of arms
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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2
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Funding
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Birjand University of Medical Sciences
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Inclusion age min
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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18
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Inclusion age max
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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100
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Countries
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Iran
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Type of patients
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Severe/critical disease at enrollment
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Severity scale
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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7: Severe/critical disease at enrollment
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Total sample size
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
40
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primary outcome
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Percentage of blood oxygen saturation (SPO2)
Arterial blood oxygen pressure in the analysis of blood gases Pao2
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Notes
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Phase
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Phase 3
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Arms
Last imported at : Aug. 13, 2022, 7:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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[{"arm_notes": "", "treatment_id": 2337, "treatment_name": "Plasmapheresis", "treatment_type": "Life support", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]
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