| Trial registration number
|
IRCT20220509054793N1 |
Full text link
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
http://en.irct.ir/trial/63426
|
First author
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Mohsen Tafaghodi
|
Contact
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
vcresearch@mums.ac.ir
|
Registration date
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
2022-06-02
|
Recruitment status
Last imported at : June 22, 2023, 4 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Completed
|
Study design
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
RCT
|
Allocation
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Randomized
|
Design
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Parallel
|
Masking
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Blind label
|
Center
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
multi-center
|
Study aim
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Treatment
|
Inclusion criteria
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Patients with COVID-19 infection base on clinical manifestations, chest CT scan and PCR test results
Age over 18 years
The oxygen saturation of patient is 85 percent or greater at rest
|
Exclusion criteria
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
having chronic lung disease
Pregnant women
Having autoimmune disease
History of allergy to the seaweed or its derivatives
History of bronchospasm after using of N-acetylcysteine
Having chronic liver disease
History of phenylketonuria
Having bleeding (Massive hemoptysis, gastrointestinal bleeding, epistaxis, purpura, ecchymosis)
Neutrophil count of less than 500 mmc
A platelet count of less than 2000 mmc
Having acute hepatitis
|
Number of arms
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
2
|
Funding
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Mashhad University of Medical Sciences
|
Inclusion age min
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
18
|
Inclusion age max
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
100
|
Countries
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Iran
|
Type of patients
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Mild/moderate disease at enrollment
|
Severity scale
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
2: Mild/moderate disease at enrollment
|
Total sample size
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
60
|
primary outcome
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
The duration of hospitalization
Improvement rate of clinical symptoms such as dyspnea and fever
Possibility of hospitalization in ICU
Mortality rate
|
Notes
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
|
Phase
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Phase 1/Phase 2
|
Arms
Last imported at : June 2, 2022, 1:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
[{"arm_notes": "", "treatment_id": 2520, "treatment_name": "Arthrospira+n-acetylcysteine", "treatment_type": "Vitamins and dietary supplements+respiratory agents", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]
|