COVID-19 trials registries data warehouse

http://www.chictr.org.cn/showproj.aspx?proj=170248

Qu Jie-Ming

liqingyun68@163.com

2022-05-19

Recruiting

RCT

Randomized

Parallel

Not reported

multi-center

Treatment

1.Male and female patients aged between 18 and 80 years old (inclusive). 2.Diagnosed as general type of COVID-19 according to the criteria of Scheme for Diagnosis and Treatment of 2019 Novel Coronavirus Pneumonia (Trial Version 9). 3.Patients who are willing to participate and provided written informed consent form.

1.Diagnosed as mild, severe, critical or asymptomatic type of COVID-19. 2.Subjects in the treatment or active stage of malignant tumor. 3.Patients who are intolerable to inhalation treatment. 4.People with mental disorders or cognitive impairment who are unable to provide consent. 5.Patients with any immunodeficiency requiring chronic treatment with any corticosteroid or other immunosuppressants. 6.Complicate serious primary diseases such as heart, liver, kidney, and hematopoietic diseases, acute exacerbation phase of chronic obstructive pulmonary disease, or acute attack of bronchial asthma. 7.Patients who are using any non-expectorant antioxidant drug, including large doses of vitamin C and vitamin E. 8.Patients who are participating any other clinical study of any investigational drug or medical device. 9.Pregnant or lactating women. 10.Any other condition judged as inappropriate to participate in this study by the investigator.

2

Ruijin Hospital; Shanghai Jiao Tong University School of Medicine

18

80

China

Moderate disease at enrollment

3: Moderate disease at enrollment

188

Time to negative viral nucleic acid detection from the start of the study treatment.;

| Declared number of arm (2.0) differs from found arms (3.0)

Phase 0

[{"arm_notes": "", "treatment_id": 605, "treatment_name": "Hydrogen-oxygen nebulizer", "treatment_type": "Gas inhalation", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 1235, "treatment_name": "Standard oxygen", "treatment_type": "Respiratory support", "pharmacological_treatment": "Non pharmacological treatment"}]