COVID-19 trials registries data warehouse

http://ensaiosclinicos.gov.br/rg/RBR-6wgwxsy

Evônio Campelo

evoniocampelo55@gmail.com

2022-03-14

Not recruiting

RCT

Randomized

Parallel

Blind label

multi-center

Treatment

outpacients with positive diagnosis for COVID-19

Patients with indication for hospital admission, patients with other protease inhibitors, pregnant, infants, more than 5 days from the onset of symptoms, HIV positive patients

3

Hospital das Clínicas da Universidade Federal de Pernambuco

18

100

Brazil

Mild disease at enrollment

1: Mild disease at enrollment

953

To evaluate the number of hospitalizations; verified by the percentage of hospitalization of the experimental and control groups; based on a finding of a variation of at least 5% in pre- and post-intervention measurements.;To evaluate hospital discharge rate; verified by the percentage of discharge rate of the experimental and control groups; based on a finding of a variation of at least 5% in pre- and post-intervention measurements.;To evaluate hospital death rate; verified by the percentage of death rate of the experimental and control groups; based on a finding of a variation of at least 5% in pre- and post-intervention measurements.

Phase 2

[{"arm_notes": "", "treatment_id": 2427, "treatment_name": "Atazanavir+doxycycline+ritonavir", "treatment_type": "Antivirals+antibiotics", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 1422, "treatment_name": "Atazanavir+ritonavir", "treatment_type": "Antivirals", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]