COVID-19 trials registries data warehouse

http://en.irct.ir/trial/60751

Vice President for Research and Technology

Info@qums.ac.ir

2022-01-16

Completed

RCT

Randomized

Parallel

Blind label

single-center

Treatment

A positive PCR test for a new coronavirus Having an involvement in a CT scan of the lungs and a definitive diagnosis by the treating physician that the person is infected Therefore, people whose confirmed results of this virus are confirmed and who have 2 or more of the following symptoms will be studied in the following study: Including: Patients with pulmonary involvement of 50% and above (severe cases) (sometimes closed At the discretion of the physician and the patient's condition, lower lung involvement is also a criterion for hospitalization (moderate cases), 90 <O2 saturation <94 (moderate to severe cases) and o2 saturation <90 (severe cases), sub-cough symptoms (visual assessment criteria) Sore throat (patient report), headache (patient report), nasal congestion (patient report), fever (temperature above 37.3), body aches and pains (patient report), fatigue (patient report)

Patients suspected of having a bacterial respiratory infection at the beginning of the study Patients with serious chronic diseases. Pregnant women Patients with HIV Patients with cancer Patients with vascular disease Patient with endocrine disease Patients who become infected during studying

2

Qazvin University of Medical Sciences

18

70

Iran

Moderate/severe disease at enrollment

4: Moderate/severe disease at enrollment

50

Cough chest pain shortness of breath O2 saturation level number of days with tachypnea fever fibrinogen levels di-dimer ROS laboratory indicators duration of possible need for use of mechanical lung ventilation systems survival rate of patients

Phase 2

[{"arm_notes": "", "treatment_id": 93, "treatment_name": "Antioxidant therapy", "treatment_type": "Others pharmacological treatment", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]