| Trial registration number
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IRCT20210709051824N1 |
Full text link
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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http://en.irct.ir/trial/57516
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First author
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Seyed Jalil Hoseini
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Contact
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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mhrhrc@yahoo.com
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Registration date
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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2021-12-08
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Recruitment status
Last imported at : Feb. 20, 2022, 5:42 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Completed
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Study design
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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RCT
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Allocation
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Randomized
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Design
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Parallel
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Masking
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Blind label
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Center
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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single-center
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Study aim
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Treatment
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Inclusion criteria
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Patients with acute or chronic renal failure, with a definitive diagnosis of Covid 19, over the age of 18 years, and lung involvement above 20% or hypoxia (oxygen saturation less than or equal to 93%)
Definitive diagnosis of Covid 19
Over the age of 18 years
Pulmonary involvement caused by Covid 19
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Exclusion criteria
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Previous history of COVID-19 infection and heart disease and receiving Remdesivir
History of lung disease
History of liver disease (such as hepatitis, cirrhosis)
History of underlying diseases other than renal impairment that contribute to poor prognosis and increased mortality following coronary heart disease (eg, heart failure, active cancer, advanced diabetes with severe macrovascular and microvascular complications, previous stroke)
Immunosuppressive use except in the field of kidney transplantation
Prohibition of Ramdesivir (except low GFR)
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Number of arms
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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2
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Funding
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Men's Health and Reproductive Health Research Center(MHRHRC)
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Inclusion age min
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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18
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Inclusion age max
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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100
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Countries
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Iran
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Type of patients
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Moderate/severe disease at enrollment
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Severity scale
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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4: Moderate/severe disease at enrollment
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Total sample size
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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100
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primary outcome
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Red blood cell count
Platelet count
White blood cell count
Medium platelet volume
Erythrocyte Sedimentation Rate
CRP
AST
ALT
International Normalized Ratio(INR)
Bilirubin
Alkaline phosphatase
Cratinin
O2 Saturation
lymphocyte count
Neutrophil count
Duration of hospitalization
Result of hospitalization(Death or discharge)
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Notes
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Phase
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Phase 3
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Arms
Last imported at : Dec. 9, 2021, 1:30 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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[{"arm_notes": "", "treatment_id": 1099, "treatment_name": "Remdesivir", "treatment_type": "Antivirals", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]
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