| Trial registration number
|
IRCT20150221021159N7 |
Full text link
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
http://en.irct.ir/trial/58978
|
First author
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Shaghayegh Haghjou Javanmard
|
Contact
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
research@mui.ac.ir
|
Registration date
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
2021-11-10
|
Recruitment status
Last imported at : April 21, 2022, 1:03 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Completed
|
Study design
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
RCT
|
Allocation
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Randomized
|
Design
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Parallel
|
Masking
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Open label
|
Center
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
single-center
|
Study aim
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Treatment
|
Inclusion criteria
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Age 18 years or older
Diagnosis of COVID-19 by RT PCR test and CT scan of the lung and the opinion of the specialist physician
Hospitalization in the intensive care unit
Full consent and acceptance of the patient or their legal guardian to recruit in the study
Possibility to follow the patient for at least 7 days
|
Exclusion criteria
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Contraindications to the use of atorvastatin include allergic reactions to the drug, active liver disease or persistent and unexplained increase in liver enzymes, pregnancy and lactation, severe hepatic or renal insufficiency (clcr <30 ml / min)
Malignancy or underlying immunodeficiency or concomitant use of immunosuppressive drugs
Intubated patient under care with mechanical ventilation
|
Number of arms
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
2
|
Funding
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Esfahan University of Medical Sciences
|
Inclusion age min
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
18
|
Inclusion age max
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
100
|
Countries
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Iran
|
Type of patients
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Critical disease at enrollment
|
Severity scale
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
8: Critical disease at enrollment
|
Total sample size
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
60
|
primary outcome
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Clinical improvement of COVID-19
|
Notes
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
|
Phase
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Phase 3
|
Arms
Last imported at : Nov. 10, 2021, 4:03 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
[{"arm_notes": "", "treatment_id": 137, "treatment_name": "Atorvastatin", "treatment_type": "Metabolic agents", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]
|