| Trial registration number
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IRCT20200506047323N8 |
Full text link
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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http://en.irct.ir/trial/56388
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First author
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Teamur Aghamolaei
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Contact
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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mail@hums.ac.ir
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Registration date
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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2021-05-24
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Recruitment status
Last imported at : Sept. 21, 2021, 2:30 p.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Completed
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Study design
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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RCT
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Allocation
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Randomized
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Design
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Parallel
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Masking
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Blind label
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Center
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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multi-center
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Study aim
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Treatment
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Inclusion criteria
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Age between 18 and 80 years
Positive polymerase chain reaction (PCR) test for COVID-19
Hospitalized
Signing informed consent and willingness of study participant to accept randomization to any assigned treatment a
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Exclusion criteria
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Contraindications epinephrine including, hemorrhagic CVA, TIA, and acute MI
Heart rate > 100
History of allergy to epinephrine
Pregnancy and breastfeeding
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Number of arms
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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2
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Funding
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Bandare-abbas University of Medical Sciences
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Inclusion age min
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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18
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Inclusion age max
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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80
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Countries
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Iran
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Type of patients
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Moderate/severe/critical disease at enrollment
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Severity scale
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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5: Moderate/severe/critical disease at enrollment
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Total sample size
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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84
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primary outcome
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Clinical symptoms
Oxygen saturation
Pulmonary imaging finding
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Notes
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Phase
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Phase 2/Phase 3
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Arms
Last imported at : May 25, 2021, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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[{"arm_notes": "Treatment group will receive the intratracheal epinephrine for intubated patients, and nebulizer form of epinephrine for non-intubated patients at a dose of 200 micrograms three times a day for five days, in addition to the standard treatment", "treatment_id": 470, "treatment_name": "Epinephrine", "treatment_type": "Cardiovascular agents", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]
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