COVID-19 trials registries data warehouse

http://en.irct.ir/trial/56149

Shaghayegh Haghjou

sh_haghjoo@med.mui.ac.ir

2021-05-13

Completed

RCT

Randomized

Parallel

Blind label

single-center

Treatment

Willingness to participate in the study Age 20-80years Diagnosis of Covid-19 based on clinical findings and PCR findings Gastrointestinal tract with normal function and intestinal nutrition criteria

Age less than 20 and more than 80 years Sensitivity to plant products such as turmeric and pepper Impossibility of intestinal feeding in the first 48 hours of admission Patients who are hospitalized in the intensive care unit for less than 48 hours. Patients who are expected to die within 12 hours of admission to the intensive care unit. Patients who do not have an indication for intestinal nutrition on the first day and are confirmed and predicted based on the diagnosis of the intensive care unit that they will not be able to receive intestinal nutrition in the future. (Nausea, persistent vomiting, ileus, intestinal obstruction, uncontrolled diarrhea (> 500 ml per day), high-output fistula (> 500 ml per day), intestinal inaccessibility, incomplete resuscitation and hemodynamic instability Patients with BMI <18.5kg / m2 admitted to the intensive care unit. Patients who receive nutritional support through complete intravenous feeding Patients with a history of underlying disease such as congenital and immune disorders, renal and hepatic insufficiency and pancreatitis.Community Verified icon Taking anticoagulants such as heparin, warfarin, aspirin, etc. Pregnancy and lactation Severe septic shock or sepsis Dissatisfaction of the patient or her legal guardian

2

Esfahan University of Medical Sciences

20

80

Iran

Critical disease at enrollment

8: Critical disease at enrollment

50

Body temperature hs-CRP Duration of hospitalization severity and number of coughs ALT AST LDH BUN creatinine CBC Albumin Blood sugar ESR NUTRIC score

Phase 3

[{"arm_notes": "", "treatment_id": 1962, "treatment_name": "Curcumin+piperin", "treatment_type": "Vitamins and dietary supplements", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]