| Trial registration number
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IRCT20190804044429N4 |
Full text link
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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http://en.irct.ir/trial/52284
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First author
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Majid Saeedi
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Contact
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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majsaeedi@gmail.com
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Registration date
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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2020-11-25
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Recruitment status
Last imported at : Dec. 20, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Completed
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Study design
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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RCT
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Allocation
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Randomized
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Design
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Parallel
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Masking
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Blind label
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Center
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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single-center
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Study aim
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Treatment
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Inclusion criteria
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Inclusion criteria are adults over the age of 18 with a diagnosis of COVID-19 based on clinical criteria (presence of any symptoms of cough, shortness of breath, fever, and CT scan of the lung for evidence of involvement consistent with COVID-19 infection) or PCR.
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Exclusion criteria
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
History of allergy to any drugs of therapeutic regimen
pregnancy and lactation
renal and hepatic disease
History of cerebral or ocular bleeding
Glomerular infiltration less than 30 ml / min
History of use of pentoxifylline
Symptoms start more than 14 days before
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Number of arms
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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2
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Funding
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Mazandaran University of Medical Sciences
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Inclusion age min
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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18
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Inclusion age max
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
100
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Countries
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Iran
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Type of patients
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Moderate disease at enrollment
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Severity scale
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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3: Moderate disease at enrollment
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Total sample size
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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60
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primary outcome
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
Clinical response to therapeutic regimen by respiratory rate
Clinical response to therapeutic regimen by blood oxygen saturation
Clinical response to therapeutic regimen by fever recovery
therapeutic regimen safety
Clinical response to therapeutic regimen by LDH level reduction
Clinical response to therapeutic regimen by CRP level reduction
Clinical response to therapeutic regimen by lymphocyte count recovery
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Notes
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
|
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Phase
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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Phase 2/Phase 3
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Arms
Last imported at : Nov. 26, 2020, 1 a.m.
Source : Iranian Registry of Clinical Trials (IRCT)
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[{"arm_notes": "", "treatment_id": 971, "treatment_name": "Pentoxifylline", "treatment_type": "Cardiovascular agents", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]
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