COVID-19 trials registries data warehouse

http://en.irct.ir/trial/51086

Leila Masoudi Yekta

masoudiyekta@yahoo.com

2020-11-11

Completed

RCT

Randomized

Parallel

Open label

single-center

Treatment

Individuals over 18 years of age whose covid-19 disease has been confirmed by PCR test (PCR specification of the test from the Iranian manufacturer - Pishtaz Teb and performed by molecular method) and clinically severely ill o2sat below 90% despite receiving oxygen Severe bilateral pulmonary involvement Satisfaction to participate in the study Failure to receive any medication other than the standard protocol approved by the National Corona Therapy

History of drug allergies to similar compounds Pregnancy and lactation Infection with other microbial or viral infections History of heart disease

2

Dezfoul University of Medical Sciences

18

100

Iran

Severe disease at enrollment

6: Severe disease at enrollment

82

Clinical efficacy according to clinical response based on blood oxygen saturation LDH levels Duration of hospitalization Mortality rate Changes in liver enzymes Clinical efficacy of treatment regimen based on changes in respiratory rate

Phase 3

[{"arm_notes": "", "treatment_id": 672, "treatment_name": "Interferon beta 1b", "treatment_type": "Interferons", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]