COVID-19 trials registries data warehouse

http://en.irct.ir/trial/51482

Dr.Mahood reza Masoudi

ssm@sirums.ac.ir

2020-11-08

Completed

RCT

Randomized

Parallel

Blind label

single-center

Treatment

COVID-19 virus infection by RT-PCR in non-hospitalization and hospitalization patients G6PD sufficient in non-hospitalization and hospitalization patients Lack of clinical response to routine outpatient treatment in non-hospitalization and hospitalization patients Clinical symptoms (fever, cough, myalgia, shortness of breath, digestive problems) in non-hospitalization and hospitalization patients Age over 12 years in non-hospitalization and hospitalization patients Patient satisfaction in non-hospitalization and hospitalization patients Lymphocytes less than 15%, respiratory distress, lung involvement on CT scan, oxygen level less than 93%, unstable vital signs, severe gastrointestinal symptoms and oral intolerance, underlying disease Except for exclusion cases hospitalization patients

Allergy to oral supplements and high doses of vitamin C Reluctance to continue participating in the trial for any reason Patients admitted to the intensive care unit (ICU) (patients who have been admitted to the ICU since admission) Pregnant and lactating lady Patients with seizures Dialysis patients

2

Sirjan Faculty of Medical Science

12

100

Iran

No restriction on type of patients

0: No restriction on type of patients

100

LDH CBC diff Na/K/Ca CRP ESR1 Weakness and nausea Lung involvement

Phase 3

[{"arm_notes": "", "treatment_id": 2205, "treatment_name": "Artemisinin+hesperidin+n-acetylcysteine+noscapine+vitamin c", "treatment_type": "Antimalarials+cardiovascular agents+respiratory agents+central nervous system agents+vitamins and dietary supplements", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]