COVID-19 trials registries data warehouse

http://en.irct.ir/trial/48153

Afshin Zarghi

mpd@sbmu.ac.ir

2020-05-31

Completed

RCT

Randomized

Parallel

Open label

single-center

Treatment

Patients between 18 and 65 years old Laboratory COVID-19 confirmed with RT-PCR Mild to moderately ill patients Patients with PaO2/FiO2 between 100-300 Signed the consent form

Acute or chronic renal impairment (Creatinin rise more than 3 units in the last 48 hours and/or GFR less than 30 mL/min) Chronic liver disease (Rise in LFTs more than 5 times and/or 3 times rise in LFTs in symptomatic patients and/or Child pugh C,D) Allergy to corticosteriods while being injected with extravasation and signs of anaphylactic shock. Patients with hyperglycemia Pregnancy and lactation

2

Shahid Beheshti University of Medical Sciences

18

None

Iran

Mild/moderate disease at enrollment

2: Mild/moderate disease at enrollment

48

Need for invasive mechanical ventilation Death

Phase 2/Phase 3

[{"arm_notes": "", "treatment_id": 400, "treatment_name": "Dexamethasone", "treatment_type": "Corticosteroids", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]