COVID-19 trials registries data warehouse

http://en.irct.ir/trial/47244

Mohammad Ali Sahraian

Vcr@tums.ac.ir

2020-04-20

Completed

RCT

Randomized

Parallel

Open label

single-center

Treatment

- Obtaining informed consent from patient or patient’s legal proxy for inclusion in this study.- Patients must be over 18 years of age- A documented positive PCR test for SARS-CoV-2 or one of the following criteria:1. Compelling clinical symptoms associated with a covid-19 infection; including: fever, dry cough and dyspnea2. A typically involvement of lungs observed in HRCT or Spiral CT scanning that can be strongly attributed to a covid-19 pneumonia3. Patients that have developed known complications of a covid-19 infection such as acute respiratory distress syndrome (ARDS) or myocarditis.

pregnancy or nursing Patients whose covid-10 infection has not been proven and have symptoms that can be attributed to either the common cold or influenza and/or have had a positive PCR test for influenza. known allergy to chloroquine or hydroxylchloroquine retinopathy G6PD deficiency prolonged QT interval severe heart failure Pacemaker implantation cardiac arrhythmia

2

Tehran University of Medical Sciences

18

None

Iran

No restriction on type of patients

0: No restriction on type of patients

110

peripheral capillary oxygen saturation Admission duration Fever Need to ICU admission

Phase 3

[{"arm_notes": "", "treatment_id": 165, "treatment_name": "Azithromycin", "treatment_type": "Antibiotics", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]