COVID-19 trials registries data warehouse

http://en.irct.ir/trial/47468

Mohsen Tafaghodi

tafaghodim@mums.ac.ir

2020-04-25

Completed

RCT

Randomized

Parallel

Blind label

single-center

Treatment

Clinical or laboratory diagnosis of mild to moderate covid-19 age between 18-85 y sign of written consent

use of protease inhibitors like kaletra history of allergy to colchicine pregnancy and lactation hepatic failure (child pugh C), kidney failure (GFR<30 ml/min), or heart failure with EF<40% concomitant use of CYP3A4 or pgp potent inhibitors or inducers concomitant use of statins except rosuvastatin active GI disturbances like active peptic ulcers transmission of patients to ICU ward or his/her intubation patients on colchicine for behcet disease or Mediterranean fever or gout patients with history of neuromuscular disease or chronic diarrhea or malabsorption

2

Mashhad University of Medical Sciences

18

85

Iran

Mild/moderate disease at enrollment

2: Mild/moderate disease at enrollment

40

fever clinical response to treatment (including improvement of cough, myalgia, headache, Olfactory and taste disorders) radiologic response laboratory response drug adverse reaction

Phase 3

[{"arm_notes": "", "treatment_id": 310, "treatment_name": "Colchicine", "treatment_type": "Metabolic agents", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]