COVID-19 trials registries data warehouse

http://en.irct.ir/trial/50556

Dr Mohammad Samiei

Samiei.moh@gmail.com

2020-09-14

Completed

RCT

Randomized

Parallel

Blind label

single-center

Prevention

18 Years to 80 years old Both genders Having household contact or contact in less than 1.5 meters for more than one hour, or exposed without facemask with a COVID-19 case confirmed with RT-PCR or with clinical or radiographic evidence of pneumonia, acute respiratory distress syndrome (ARDS) Free of the COVID-19 disease symptoms (fever, cough, dyspnea, difficulty breathing, sore throat, severe fatigue, headache, GI symptoms) Free from chronic respiratory or other illnesses with symptoms confused with symptoms of COVID-19 disease Signed consent form

Less than 18 years Severe renal failure Severe liver disease Pregnant or breastfeeding woman or with a positive pregnancy test result Subjects on immune-modulating drugs for other diseases subjects on other clinical trials for COVID-19 within 30 days before or after randomization Subjects in other drug clinical trial Having an allergy to bromhexine hydrochloride or its ingredients

2

Tabriz University of Medical Sciences

18

80

Iran

Close contacts to covid patients

N/A

3500

Test for the presence or absence of corona virus nucleic acid Serum levels of IgM and IgG

Phase 2

[{"arm_notes": "", "treatment_id": 240, "treatment_name": "Bromhexine hydrochloride", "treatment_type": "Respiratory agents", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]