COVID-19 trials registries data warehouse

http://ensaiosclinicos.gov.br/rg/RBR-2ggx7sm

Marcus Jones

mhjones@pucrs.br

2022-01-11

Not recruiting

RCT

Randomized

Parallel

Open label

multi-center

Treatment

Age = 18 years with or without comorbidity, COVID-19 mild (WHO clinical progression scale = 2), Symptoms duration less than 72 hours, Laboratory confirmation of COVID-19, by detecting the viral antigen in respiratory secretions, collected by nasal swab (PanbioTM COVID-19 Ag, Abbott®), Signature, by the patient or a legal representative, of the informed consent form

Pregnant women, Patients in palliative care, Refusal to sign the TCLEP, Patients immunized with two doses of the immunizers, with the exception of individuals over 80 years of age who have been immunized with Coronavac vaccine for more than 6 months, Patients with suspected reinfection, Allergic reactions prior to plasma transfusion

2

Ministério da Ciência; Tecnologia e Inovações

18

100

Brazil

Mild disease at enrollment

1: Mild disease at enrollment

0

Number of patients requiring hospitalization for complications of SARS-CoV-2 infection on day 28. Measured by monitoring the participant's medical record in case of hospital admission and compared to the control group (no treatment)

Not reported

[{"arm_notes": "", "treatment_id": 322, "treatment_name": "Convalescent plasma", "treatment_type": "Convalescent plasma", "pharmacological_treatment": "Biological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]