COVID-19 trials registries data warehouse

https://clinicaltrials.gov/show/NCT04441424

Ahmed S Abdulamir, PhD

Not reported

2020-06-22

Completed

RCT

Randomized

Parallel

Open label

single-center

Treatment

inclusion criteria: - 49 critically-ill covid-19 patients are included. - all of the patients were with pneumonia and residing in rcu - age ≥ 18 y - with dyspnea and oxygen saturation less than 90% in resting state. - at their first 3 days in rcu either receiving o2 therapy, c-pap, or on ventilators. - all of the patients were residing in infectious diseases wards before being transferred to rcu.

- the exclusion criteria of the covid-19 patients were: - previous allergic history to plasma or its ingredients such as sodium citrate. - cases with serious general conditions, such as severe organ dysfunction, that are not suitable for transfusion. - very late stage of the acute respiratory distress (ards) where convalescent plasma (cp) has proved to be of low therapeutic benefit

2

Alkarkh Health Directorate-Baghdad

18

100

Iraq

Critical disease at enrollment

8: Critical disease at enrollment

49

Death versus survival of treated patients

None

Not reported

[{"arm_notes": "", "treatment_id": 322, "treatment_name": "Convalescent plasma", "treatment_type": "Convalescent plasma", "pharmacological_treatment": "Biological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]