COVID-19 trials registries data warehouse

https://www.isrctn.com/ISRCTN49832318

Not reported

rbihariesingh@azp.sr

2021-09-02

Recruiting

RCT

Randomized

Parallel

Open label

unclear

Treatment

1. COVID-19 positive patients who have understood and signed the informed consent 2. Aged =18 years 3. Hospital admitted patients with moderate COVID-19 to the non-ICU ward: Laboratory confirmed infection with COVID-19.

1. Severe or life threatening respiratory disease upon admission 2. Viral pneumonia with other viruses besides COVID-19 3. Ineligible for Convalescent Plasma Therapy 4. Participation in other studies. 5. Other circumstances in which the investigator determined that the patient is not suitable for the clinical trial 6. Refusal of informed consent study participation by Donor and/or Patient 7. Known IgA deficiency 8. Medical conditions in which receipt of 220 ml volume may be detrimental to the patient (e.g.decompensated congestive heart failure) 9. Females who are pregnant or breast feeding

2

Academic Hospital Paramaribo

18

100

Suriname

Moderate disease at enrollment

3: Moderate disease at enrollment

210

Development of severe respiratory disease; defined as a respiratory rate of 30 breaths per minute or more; an oxygen saturation of less than 93% while the patient was breathing ambient air; or both; measured for up to 60 days from baseline.

Not reported

[{"arm_notes": "", "treatment_id": 322, "treatment_name": "Convalescent plasma", "treatment_type": "Convalescent plasma", "pharmacological_treatment": "Biological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]