COVID-19 trials registries data warehouse

http://www.chictr.org.cn/showproj.aspx?proj=53028

Weihui Fu

fuweihui4011@163.com

2020-12-11

Recruiting

RCT

Randomized

Parallel

Not reported

single-center

Treatment

1. Aged from 18 to 70 years old, 2.The diagnostic criteria of subjects clearly defined as SARS-CoV-2 infected pneumonia shall be based on the criteria of severe patients stipulated in the Novel Coronavirus Infected Pneumonia Protocol (Trial version vii) issued by the National Health Commission, 3. Patients can receive aerosol inhalation, 4. Consent to sign a written informed statement prior to the beginning of the study.

1. Pneumonia caused by other viruses, except for 2019-nCov, 2. Clear bacterial infection, 3. Subjects who have used antiviral drugs and may need another antiviral treatment during the study, 4. There are serious non-infectious pulmonary diseases, including tuberculosis, pulmonary edema and pulmonary embolism, 5. Severe liver and kidney dysfunction, 6. Participating in other clinical studies within 30 days before administration, 7. Allergic to type 1 interferon, 8. Pregnant or lactating women, 9.In any other case, if the investigator thinks it is not suitable for the trial, or it may increase the risk of the subject or interfere with the clinical trial.

2

Shanghai Public Health Clinical Center

18

70

China

Severe disease at enrollment

6: Severe disease at enrollment

20

Viral load;Clinical Symptoms (Fever; Cough...);Inflammation;Pulmonary imaging;In-hospital days;

| Declared number of arm (2.0) differs from found arms (3.0)

Phase 0

[{"arm_notes": "", "treatment_id": 43, "treatment_name": "Aerosol inhalation", "treatment_type": "Gas inhalation", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]