COVID-19 trials registries data warehouse

http://www.ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=48195

Irfan Ismail Ayub

irfanismailayub@gmail.com

2020-11-24

Not recruiting

RCT

Randomized

Parallel

Open label

multi-center

Long covid

1. All patients diagnosed with COVID 19 based on positive result on SARS-CoV2 RT-PCR or CBNAAT from nasopharyngeal or oropharyngeal swab or secretions. <br/ >2. More than two weeks, but less than six weeks have lapsed after the above diagnostic positive result. <br/ >3. A repeat nasopharyngeal or oropharyngeal swab test (either SARS-CoV2 RT-PCR or CBNAAT) performed at two weeks or later, after earlier positive result, is now negative. <br/ >4. CT scan of thorax performed after two weeks and less than six weeks after the first positive result, shows features of organizing pneumonia. <br/ > <br/ >Organizing pneumonia on CT scan of thorax is diagnosed when, one or more of the following features are identified on the CT scan images of thorax: <br/ >1.Unilateral or bilateral basal subpleural lobar, segmental or perilobular consolidation <br/ >2.Halo sign <br/ >3.Reverse halo sign or atoll sign <br/ >4.Target sign or bulls-eye sign or double halo sign <br/ >

1.Patient is unwilling to provide consent <br/ >2.Patients with preexisting parenchymal or interstitial lung disease <br/ >

3

SELF DrIrfan Ismail Ayub

18

65

India

Patients recovered from covid

N/A

120

Percentage of patients with complete resolution of lung findings at third month of follow up.Timepoint: Three months of follow up

| Declared number of arm (3.0) differs from found arms (4.0)

Not reported

[{"arm_notes": "250mg", "treatment_id": 292, "treatment_name": "Clarithromycin", "treatment_type": "Antibiotics", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "500mg", "treatment_id": 292, "treatment_name": "Clarithromycin", "treatment_type": "Antibiotics", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]