COVID-19 trials registries data warehouse

http://www.ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=47280

Dr shobha

shobha_bhushan@yahoo.co.in

2020-09-09

Not recruiting

RCT

Randomized

Parallel

Blind label

single-center

Treatment

I. All patients with age more than 18 years who are asymptomatic,mild cases of COVID-19 who are under home isolation <br/ >II. COVID-19 positive cases under home isolation who consents for the study <br/ >III. Household contacts of home isolated COVID-19 patients who are able to understand and follow/perform the interventions. <br/ >

i. Patients with known history of immuno-suppressive disorders <br/ >ii. Patients with known history of hyperthyroidism and other thyroid diseases and with symptoms suggestive of thyroid dysfunction like tremors, palpitation, heat/cold intolerance, lethargy, menstrual irregularities etc <br/ >iii. Pregnant and lactating women <br/ >iv. Patients with nasal polyps, recurrent nasal bleeding <br/ >v. Patients with known allergy to iodine and its compounds and on Lithium therapy <br/ >

8

Dr Shobha

18

100

India

Mild disease at enrollment

1: Mild disease at enrollment

80

1) Reduction in severity of symptoms (VAS; temperature etc) in mild cases <br/ >2) Early negativity of the RT PCR in nasopharyngeal swab among the intervention group when compared to the controls <br/ >3) Reduction in transmission of infection among household members of COVID-19 patient <br/ >Timepoint: 1) Baseline assessment and daily follow up of symptoms till 21 days <br/ >2) Baseline swab test and swab test once every 3 days till two successive tests are negative <br/ >3) Baseline symptomatic assessment of contacts and daily follow up of evolution of symptoms till 21 days and one swab test between 5th to 10th days of contact to assess transmission pattern. <br/ >

Not reported

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