COVID-19 trials registries data warehouse

https://www.thaiclinicaltrials.org/show/TCTR20200404004

Suvimol Niyomnaitham

suvimol.niy@mahidol.edu

2020-04-04

Not recruiting

RCT

Randomized

Parallel

Open label

unclear

Prevention

1. Age &gt,18 years old at the time of consent 2. Male or female 3. At least one household member diagnosed with COVID-19 by RT-PCR or serology within the past 7 calendar days 4. Has a negative pregnancy test if the subject is female and pre-menopausal 5. Has provided written consent for participation, written consents from both the subject and a legal guardian

1. Has a RT-PCR test positive for SARS-CoV2 from pharyngeal or nasopharyngeal swab at baseline (they could be enrolled, and exclude later) 2. Abnormal laboratory &gt,= grade 3 3. Pregnant or planning pregnancy 4. HIV patients receiving PI therapy 5. History of glucose-6-phosphate dehydrogenase (G6PD) deficiency 6. Hypersensitivity to 4-aminoquinoline derivatives 7. Deemed ineligible as determined by the principal investigator or a co-investigator

2

Health Systems Research Institute (HSRI)

18

100

Thailand

Close contacts to covid patients

N/A

400

Seroconversion of SARS-CoV2 Day 21 Rate of seroconversion

Phase 4

[{"arm_notes": "", "treatment_id": 279, "treatment_name": "Chloroquine", "treatment_type": "Antimalarials", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 1369, "treatment_name": "Vitamin c", "treatment_type": "Vitamins and dietary supplements", "pharmacological_treatment": "Pharmacological treatment"}]