COVID-19 trials registries data warehouse

http://ensaiosclinicos.gov.br/rg/RBR-7d7ngw

Jorge Luis Dos Anjos

jorgelmanjos@hotmail.com

2020-08-07

Recruiting

RCT

Randomized

Parallel

Open label

unclear

Treatment

Patients will be included in surveys over the age of 18, are available hemodynamically, with arterial oxygen saturation greater than or equal to 94%, temperature below 38.5 degrees, Respiratory rate below 30 breaths per minute, who are on spontaneous ventilation to the environment or using oxygen support.

Patients who do not have a confirmed diagnosis of COVID-19 will be excluded, patients with severe acute arrhythmias, with a history of hemodynamic instability or recent cardiorespiratory arrest, Recent cardiothoracic surgery or unstable chest, Polytrauma with unstabilized fractures, Pregnant women, Recent abdominal surgery or stoma formation.

2

Hospital Geral Roberto Santos

18

100

Brazil

Mild/moderate disease at enrollment

2: Mild/moderate disease at enrollment

0

Reduction of the need for orotracheal intubation and invasive mechanical ventilation in patients submitted to early prone position; verified by measuring epidemiological variables such as relative risk; absolute risk and the number needed to treat; based on the finding of a difference of at least 10 per between groups.;Fewer deaths in patients submitted to early prone position; verified by measuring epidemiological variables such as relative risk; absolute risk and the number needed to treat; based on the observation of a difference of at least 10 percent between the groups.

Phase 2/Phase 3

[{"arm_notes": "", "treatment_id": 1027, "treatment_name": "Prone position", "treatment_type": "Respiratory support", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]