[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Airway Pressure Release Ventilation: Patients will be transitioned from their previous volume assist-controlled ventilation to APRV with the following initial settings: high airway pressure (Phigh) of at the Pplat measured during previous VCV settings; not to exceed 30 cm H2O; low airway pressure (Plow) will be set at 5 cm H2O (minimal pressure level was used to prevent atelectasis per standard practice); duration of release (Tlow) will be set as 1.5 times of expiratory time constant and further adjusted to achieve 75% of peak expiratory flow rate. Thigh will be around 5s to achieve a release frequency of 10- 14/min.Control Intervention1: Low tidal volume (LTV) ventilation: In the LTV group; tidal volume target will be 6 mL/ kg PBW; with allowances for 4\u00e2??8 mL/kg PBW to minimize asynchrony between the patient and ventilator; PEEP levels will be adjusted by the ARDSnet PEEP-FiO2 table; and then tidal volume and the respiratory rate will be regulated to achieve the above target pH. When PFR is 150; PEEP will be tittered on the basis of lowest driving pressure.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Airway Pressure Release Ventilation: Patients will be transitioned from their previous volume assist-controlled ventilation to APRV with the following initial settings: high airway pressure (Phigh) of at the Pplat measured during previous VCV settings; not to exceed 30 cm H2O; low airway pressure (Plow) will be set at 5 cm H2O (minimal pressure level was used to prevent atelectasis per standard practice); duration of release (Tlow) will be set as 1.5 times of expiratory time constant and further adjusted to achieve 75% of peak expiratory flow rate. Thigh will be around 5s to achieve a release frequency of 10- 14/min.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Control Intervention1: Low tidal volume (LTV) ventilation: In the LTV group; tidal volume target will be 6 mL/ kg PBW; with allowances for 4\u00e2??8 mL/kg PBW to minimize asynchrony between the patient and ventilator; PEEP levels will be adjusted by the ARDSnet PEEP-FiO2 table; and then tidal volume and the respiratory rate will be regulated to achieve the above target pH. When PFR is 150; PEEP will be tittered on the basis of lowest driving pressure.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 51, "treatment_name": "Airway pressure release ventilation", "treatment_type": "Respiratory support", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 752, "treatment_name": "Low tidal volume (ltv) ventilation", "treatment_type": "Respiratory support", "pharmacological_treatment": "Non pharmacological treatment"}]

[{"arm_notes": "", "treatment_id": null, "treatment_name": "N/A", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Airway Pressure Release Ventilation: Patients will be transitioned from their previous volume assist-controlled ventilation to APRV with the following initial settings: high airway pressure (Phigh) of at the Pplat measured during previous VCV settings; not to exceed 30 cm H2O; low airway pressure (Plow) will be set at 5 cm H2O (minimal pressure level was used to prevent atelectasis per standard practice); duration of release (Tlow) will be set as 1.5 times of expiratory time constant and further adjusted to achieve 75% of peak expiratory flow rate. Thigh will be around 5s to achieve a release frequency of 10- 14/min.Control Intervention1: Low tidal volume (LTV) ventilation: In the LTV group; tidal volume target will be 6 mL/ kg PBW; with allowances for 4\u00e2??8 mL/kg PBW to minimize asynchrony between the patient and ventilator; PEEP levels will be adjusted by the ARDSnet PEEP-FiO2 table; and then tidal volume and the respiratory rate will be regulated to achieve the above target pH. When PFR is 150; PEEP will be tittered on the basis of lowest driving pressure.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Airway Pressure Release Ventilation: Patients will be transitioned from their previous volume assist-controlled ventilation to APRV with the following initial settings: high airway pressure (Phigh) of at the Pplat measured during previous VCV settings; not to exceed 30 cm H2O; low airway pressure (Plow) will be set at 5 cm H2O (minimal pressure level was used to prevent atelectasis per standard practice); duration of release (Tlow) will be set as 1.5 times of expiratory time constant and further adjusted to achieve 75% of peak expiratory flow rate. Thigh will be around 5s to achieve a release frequency of 10- 14/min.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Control Intervention1: Low tidal volume (LTV) ventilation: In the LTV group; tidal volume target will be 6 mL/ kg PBW; with allowances for 4\u00e2??8 mL/kg PBW to minimize asynchrony between the patient and ventilator; PEEP levels will be adjusted by the ARDSnet PEEP-FiO2 table; and then tidal volume and the respiratory rate will be regulated to achieve the above target pH. When PFR is 150; PEEP will be tittered on the basis of lowest driving pressure.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]