inclusion criteria: 1. adult aged ≥18years old 2. provide voluntary, fully informed written and signed consent before any study-related procedures are conducted 3. able to understand and comply with the relevant aspects of the study protocol 4. laboratory (rt-pcr) confirmed covid-19 infection on throat swab and/or sputum and/or lower respiratory tract samples 5. hospitalized with a resting room-air spo2 of ≤93% or pao2/fio2 ratio \<300mmhg. measurement can be taken from documented source records in the 24 hours prior to screening 6. chest imaging confirming lung involvement

inclusion criteria: 1. adult aged ≥18years old 2. provide voluntary, fully informed written and signed consent before any study-related procedures are conducted 3. able to understand and comply with the relevant aspects of the study protocol 4. laboratory (rt-pcr) confirmed covid-19 infection on throat swab and/or sputum and/or lower respiratory tract samples 5. hospitalized with a resting room-air spo2 of ≤93% or pao2/fio2 ratio \<300mmhg. measurement can be taken from documented source records in the 24 hours prior to screening 6. chest imaging confirming lung involvement

inclusion criteria: adult aged ≥18years old provide voluntary, fully informed written and signed consent before any study-related procedures are conducted able to understand and comply with the relevant aspects of the study protocol laboratory (rt-pcr) confirmed covid-19 infection on throat swab and/or sputum and/or lower respiratory tract samples hospitalized with a resting room-air spo2 of ≤93% or pao2/fio2 ratio <300mmhg. measurement can be taken from documented source records in the 24 hours prior to screening chest imaging confirming lung involvement

inclusion criteria: adult aged ≥18years old provide voluntary, fully informed written and signed consent before any study-related procedures are conducted able to understand and comply with the relevant aspects of the study protocol laboratory (rt-pcr) confirmed covid-19 infection on throat swab and/or sputum and/or lower respiratory tract samples hospitalized with a resting room-air spo2 of ≤93% or pao2/fio2 ratio <300mmhg. measurement can be taken from documented source records in the 24 hours prior to screening chest imaging confirming lung involvement

inclusion criteria: 1. adult aged ≥18years old 2. provide voluntary, fully informed written and signed consent before any study-related procedures are conducted 3. able to understand and comply with the relevant aspects of the study protocol 4. laboratory (rt-pcr) confirmed covid-19 infection on throat swab and/or sputum and/or lower respiratory tract samples 5. hospitalized with a resting room-air spo2 of ≤93% or pao2/fio2 ratio <300mmhg. measurement can be taken from documented source records in the 24 hours prior to screening 6. chest imaging confirming lung involvement

inclusion criteria: 1. adult aged ≥18years old 2. provide voluntary, fully informed written and signed consent before any study-related procedures are conducted 3. able to understand and comply with the relevant aspects of the study protocol 4. laboratory (rt-pcr) confirmed covid-19 infection on throat swab and/or sputum and/or lower respiratory tract samples 5. hospitalized with a resting room-air spo2 of ≤93% or pao2/fio2 ratio <300mmhg. measurement can be taken from documented source records in the 24 hours prior to screening 6. chest imaging confirming lung involvement