Created at Source Raw Value Validated value
Nov. 26, 2021, 10:30 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Lowest driving pressure guided PEEP: Initial PEEP would be kept at 5 cmH2O and driving pressure would be noted. PEEP would be stepped up in increments of 1 and the corresponding \u00ce?P would be checked after 1 minute. The PEEP levels at which \u00ce?P is the least would be chosen. In case the driving pressure achieved is same for more than one consecutive value of PEEP; then the lowest level of PEEP would be chosen.After 12 hours; driving pressures would be checked again and the same protocol would be followed to find the lowest \u00ce?P. If it is noted at any point that \u00ce?P increases with increase in PEEP; then PEEP would be reduced in decrements of 1 until the lowest \u00ce?P is achieved. The rest of the ventilator settings would be as per ARDSnet protocol.Control Intervention1: Conventional lung protective ventilation strategy( ARDSnet protocol): Ventilator settings used would be as per the PEEP/FiO2 combinations used in ARDSnet protocol.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Lowest driving pressure guided PEEP: Initial PEEP would be kept at 5 cmH2O and driving pressure would be noted. PEEP would be stepped up in increments of 1 and the corresponding \u00ce?P would be checked after 1 minute. The PEEP levels at which \u00ce?P is the least would be chosen. In case the driving pressure achieved is same for more than one consecutive value of PEEP; then the lowest level of PEEP would be chosen.After 12 hours; driving pressures would be checked again and the same protocol would be followed to find the lowest \u00ce?P. If it is noted at any point that \u00ce?P increases with increase in PEEP; then PEEP would be reduced in decrements of 1 until the lowest \u00ce?P is achieved. The rest of the ventilator settings would be as per ARDSnet protocol.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Control Intervention1: Conventional lung protective ventilation strategy( ARDSnet protocol): Ventilator settings used would be as per the PEEP/FiO2 combinations used in ARDSnet protocol.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "Conventional lung protective ventilation strategy( ARDSnet protocol) \nDetails: Ventilator settings used would be as per the PEEP/FiO2 combinations used in ARDSnet protocol. ", "treatment_id": 989, "treatment_name": "Physician guided peep (ardsnet protocol)", "treatment_type": "Respiratory support", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "Lowest driving pressure guided PEEP\u00a0\nDetails: Initial PEEP would be kept at 5 cmH2O and driving pressure would be noted. PEEP would be stepped up in increments of 1 and the corresponding \u0394P would be checked after 1 minute. The PEEP levels at which \u0394P is the least would be chosen. In case the driving pressure achieved is same for more than one consecutive value of PEEP, then the lowest level of PEEP would be chosen. After 12 hours, driving pressures would be checked again and the same protocol would be followed to find the lowest \u0394P. If it is noted at any point that \u0394P increases with increase in PEEP, then PEEP would be reduced in decrements of 1 until the lowest \u0394P is achieved. The rest of the ventilator settings would be as per ARDSnet protocol. ", "treatment_id": 420, "treatment_name": "Driving pressure guided positive end expiratory pressure (peep) strategy", "treatment_type": "Respiratory support", "pharmacological_treatment": "Non pharmacological treatment"}]

Nov. 13, 2021, 5:33 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "N/A", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

Oct. 26, 2020, 8:29 a.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Lowest driving pressure guided PEEP: Initial PEEP would be kept at 5 cmH2O and driving pressure would be noted. PEEP would be stepped up in increments of 1 and the corresponding \u00ce?P would be checked after 1 minute. The PEEP levels at which \u00ce?P is the least would be chosen. In case the driving pressure achieved is same for more than one consecutive value of PEEP; then the lowest level of PEEP would be chosen.After 12 hours; driving pressures would be checked again and the same protocol would be followed to find the lowest \u00ce?P. If it is noted at any point that \u00ce?P increases with increase in PEEP; then PEEP would be reduced in decrements of 1 until the lowest \u00ce?P is achieved. The rest of the ventilator settings would be as per ARDSnet protocol.Control Intervention1: Conventional lung protective ventilation strategy( ARDSnet protocol): Ventilator settings used would be as per the PEEP/FiO2 combinations used in ARDSnet protocol.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Lowest driving pressure guided PEEP: Initial PEEP would be kept at 5 cmH2O and driving pressure would be noted. PEEP would be stepped up in increments of 1 and the corresponding \u00ce?P would be checked after 1 minute. The PEEP levels at which \u00ce?P is the least would be chosen. In case the driving pressure achieved is same for more than one consecutive value of PEEP; then the lowest level of PEEP would be chosen.After 12 hours; driving pressures would be checked again and the same protocol would be followed to find the lowest \u00ce?P. If it is noted at any point that \u00ce?P increases with increase in PEEP; then PEEP would be reduced in decrements of 1 until the lowest \u00ce?P is achieved. The rest of the ventilator settings would be as per ARDSnet protocol.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Control Intervention1: Conventional lung protective ventilation strategy( ARDSnet protocol): Ventilator settings used would be as per the PEEP/FiO2 combinations used in ARDSnet protocol.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]