1. Male or female adults above 18 years (not tested in children yet) <br/ >2. Informed consent for participation in the study <br/ >3. Virological diagnosis of SARS-CoV2 infection (PCR) <br/ >4. Hospitalized due to clinical/instrumental diagnosis of COVID-19 infection <br/ >5. Oxygen saturation at rest in ambient air â?¤94% <br/ >6. Patients who are in moderate to severe ARDS as defined by PaO2/Fio2 ratio of < 200 or <br/ >more than 25% detoriation from the immediate previous value. <br/ >

1. Male or female adults above 18 years (not tested in children yet) <br/ >2. Informed consent for participation in the study <br/ >3. Virological diagnosis of SARS-CoV2 infection (PCR) <br/ >4. Hospitalized due to clinical/instrumental diagnosis of COVID-19 infection <br/ >5. Oxygen saturation at rest in ambient air â?¤94% <br/ >6. Patients who are in moderate to severe ARDS as defined by PaO2/Fio2 ratio of < 200 or <br/ >more than 25% detoriation from the immediate previous value. <br/ >

1. Male or female adults above 18 years (not tested in children yet) <br/ >2. Informed consent for participation in the study <br/ >3. Virological diagnosis of SARS-CoV2 infection (PCR) <br/ >4. Hospitalized due to clinical/instrumental diagnosis of COVID-19 infection <br/ >5. Oxygen saturation at rest in ambient air â?¤94% <br/ >6. Patients who are in moderate to severe ARDS as defined by PaO2/Fio2 ratio of < 200 or <br/ >more than 25% detoriation from the immediate previous value. <br/ >

1. Male or female adults above 18 years (not tested in children yet) <br/ >2. Informed consent for participation in the study <br/ >3. Virological diagnosis of SARS-CoV2 infection (PCR) <br/ >4. Hospitalized due to clinical/instrumental diagnosis of COVID-19 infection <br/ >5. Oxygen saturation at rest in ambient air â?¤94% <br/ >6. Patients who are in moderate to severe ARDS as defined by PaO2/Fio2 ratio of < 200 or <br/ >more than 25% detoriation from the immediate previous value. <br/ >