1. patient in a state of pregnancy. 2. require mechanical ventilation (invasive or non-invasive, including oxygen mask with reserve bag) on examination. 3. participation in any other clinical trial of an experimental treatment for covid-19. 4. at the discretion of the clinical team, progression to death is imminent and inevitable within the next 24 hours, regardless of the provision of treatments. 5. any incompatibility or allergy to the administration of plasma of human origin. 6. severe chronic kidney disease in stage 4 or requiring dialysis (that is, glomerular filtration rate \<30). 7. any condition that in the investigator's opinion limits participation in the study.

1. patient in a state of pregnancy. 2. require mechanical ventilation (invasive or non-invasive, including oxygen mask with reserve bag) on examination. 3. participation in any other clinical trial of an experimental treatment for covid-19. 4. at the discretion of the clinical team, progression to death is imminent and inevitable within the next 24 hours, regardless of the provision of treatments. 5. any incompatibility or allergy to the administration of plasma of human origin. 6. severe chronic kidney disease in stage 4 or requiring dialysis (that is, glomerular filtration rate \<30). 7. any condition that in the investigator's opinion limits participation in the study.

patient in a state of pregnancy. require mechanical ventilation (invasive or non-invasive, including oxygen mask with reserve bag) on examination. participation in any other clinical trial of an experimental treatment for covid-19. at the discretion of the clinical team, progression to death is imminent and inevitable within the next 24 hours, regardless of the provision of treatments. any incompatibility or allergy to the administration of plasma of human origin. severe chronic kidney disease in stage 4 or requiring dialysis (that is, glomerular filtration rate <30). any condition that in the investigator's opinion limits participation in the study.

patient in a state of pregnancy. require mechanical ventilation (invasive or non-invasive, including oxygen mask with reserve bag) on examination. participation in any other clinical trial of an experimental treatment for covid-19. at the discretion of the clinical team, progression to death is imminent and inevitable within the next 24 hours, regardless of the provision of treatments. any incompatibility or allergy to the administration of plasma of human origin. severe chronic kidney disease in stage 4 or requiring dialysis (that is, glomerular filtration rate <30). any condition that in the investigator's opinion limits participation in the study.

1. patient in a state of pregnancy. 2. require mechanical ventilation (invasive or non-invasive, including oxygen mask with reserve bag) on examination. 3. participation in any other clinical trial of an experimental treatment for covid-19. 4. at the discretion of the clinical team, progression to death is imminent and inevitable within the next 24 hours, regardless of the provision of treatments. 5. any incompatibility or allergy to the administration of plasma of human origin. 6. severe chronic kidney disease in stage 4 or requiring dialysis (that is, glomerular filtration rate <30). 7. any condition that in the investigator's opinion limits participation in the study.

1. patient in a state of pregnancy. 2. require mechanical ventilation (invasive or non-invasive, including oxygen mask with reserve bag) on examination. 3. participation in any other clinical trial of an experimental treatment for covid-19. 4. at the discretion of the clinical team, progression to death is imminent and inevitable within the next 24 hours, regardless of the provision of treatments. 5. any incompatibility or allergy to the administration of plasma of human origin. 6. severe chronic kidney disease in stage 4 or requiring dialysis (that is, glomerular filtration rate <30). 7. any condition that in the investigator's opinion limits participation in the study.