1. Pregnant women within 3 months of pregnancy, 2. Patients with liver and kidney disease and those with liver and kidney injury 3. Patients with blood diseases (such as leukopenia, thrombocytopenia, etc.). 4. Electrocardiogram prompting patients with severely extended QT.

1. Pregnant women within 3 months of pregnancy, 2. Patients with liver and kidney disease and those with liver and kidney injury 3. Patients with blood diseases (such as leukopenia, thrombocytopenia, etc.). 4. Electrocardiogram prompting patients with severely extended QT.