1. Patients allergic to chloroquine and hydroxychloroquine, 2. Pregnant women, 3. Patients with severe diseases of heart, lung, kidney, brain, blood and other important organs and dysfunction, 4. Patients with retinopathy, hearing loss or hearing loss, 5. Patients with severe neurological and psychiatric diseases, 6. Subjects who, in the opinion of the investigator, were unable to complete the study as required or were not suitable to participate in the study.

1. Patients allergic to chloroquine and hydroxychloroquine, 2. Pregnant women, 3. Patients with severe diseases of heart, lung, kidney, brain, blood and other important organs and dysfunction, 4. Patients with retinopathy, hearing loss or hearing loss, 5. Patients with severe neurological and psychiatric diseases, 6. Subjects who, in the opinion of the investigator, were unable to complete the study as required or were not suitable to participate in the study.