1. Aged above 18 years, 2. Able to understand the content of informed consent and willing to sign the informed consent, 3. Able and willing to complete all the secluded study process during the whole follow-up period of 6 months. 4. Negative in HIV diagnostic test, 5. Axillary temperature <=37.0 degree C, 6. Negative in serum antibodies (IgG and IgM) screening of COVID-19. 7. The BMI index 18.5-30.0, 8. General good health as established by medical history and physical examination.

1. Aged above 18 years, 2. Able to understand the content of informed consent and willing to sign the informed consent, 3. Able and willing to complete all the secluded study process during the whole follow-up period of 6 months. 4. Negative in HIV diagnostic test, 5. Axillary temperature <=37.0 degree C, 6. Negative in serum antibodies (IgG and IgM) screening of COVID-19. 7. The BMI index 18.5-30.0, 8. General good health as established by medical history and physical examination.