1) left heart failure pulmonary edema, 2) pregnancy and lactation or perinatal period, 3) liver failure MELD score >40, 4) a history of deep vein thrombosis or pulmonary embolism in the past 3 months, 5) cases that the researcher judged to be unsuitable for the group.

1) left heart failure pulmonary edema, 2) pregnancy and lactation or perinatal period, 3) liver failure MELD score >40, 4) a history of deep vein thrombosis or pulmonary embolism in the past 3 months, 5) cases that the researcher judged to be unsuitable for the group.